The Chemistry of CRISPRs & Genome Editing
Jennifer Doudna, PhD, Professor and HHMI Investigator, UC Berkeley
Date: Wednesday, November 16, 2017
Location: Chevron Technology Center, 100 Chevron Way, Richmond CA
Abstract: Gene editing with CRISPR technology is transforming biology. Understanding the underlying chemical mechanisms of RNA-guided DNA and RNA cleavage provides a foundation for both conceptual advances and technology development. I will discuss how bacterial CRISPR adaptive immune systems inspire the creation of powerful genome engineering tools, enabling advances in both fundamental biology and applications in medicine. Ethical challenges of some of these applications will also be discussed.
Bio: As an internationally renowned professor of Chemistry and Molecular and Cell Biology at U.C. Berkeley, Doudna and her colleagues rocked the research world in 2012 by describing a simple way of editing the DNA of any organism using an RNA-guided protein found in bacteria. This technology, called CRISPR-Cas9, has opened the floodgates of possibility for human and non-human applications of gene editing, including assisting researchers in the fight against HIV, sickle cell disease, and muscular dystrophy. Doudna is an Investigator with the Howard Hughes Medical Institute and a member of the National Academy of Sciences, the National Academy of Medicine, the National Academy of Inventors and the American Academy of Arts and Sciences. She is also a Foreign Member of the Royal Society and has received many other honors including the Breakthrough Prize in Life Sciences, the Heineken Prize, the BBVA Foundation Frontiers of Knowledge Award and the Japan Prize. She is the co-author with Sam Sternberg of “A Crack in Creation”, a personal account of her research and the societal and ethical implications of gene editing.
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|Seminar||The Chemistry of CRISPRs & Genome Editing|
|Date||Wednesday, November 16, 2017|
|Time||5:30PM – 7:00 PM Social
7:00PM – 8:15 PM Seminar
|Location||Chevron Technology Center, 100 Chevron Way, Richmond CA|
|Cost||$10 for members
$5 for students